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Klf13 cancer

WebJun 1, 2010 · KLF13 is a transcription factor required for the expression of several oncogenes. FGFR3 is a fibroblast growth factor receptor that initiates a signaling cascade leading to the activation of... WebOct 9, 2024 · Pancreatic cancer (PC) is generally acknowledged as one of the most malignant cancer which is difficult to diagnose and cure [ 1 ]. Despite the technology in diagnosis instrument and treatment for PC have improved, the average 5-year survival rate of PC patients remained lower than 6–8% [ 2, 3 ].

KLF13 regulates the differentiation-dependent human

Webregulation of Kruppel-like factor 13 (KLF13) is yet to be explored. The results of the present study miR-125-5paresignificantly(P … WebAs a suppressive transcription factor, KLF13 has been found to be involved in some cell processes of several cancer types. KLF13 expression was inhibited in prostate cancer while its... is airwalk still in business https://northernrag.com

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WebFeb 22, 2024 · KLF13 is predominantly expressed in heart, interacting with GATA-4 and regulating the early stage of cardiogenesis. 3 In the mice model, KLF13 deficiency … WebSep 24, 2013 · KLF2, KLF3, KLF4, KLF11, KLF13, KLF14, KLF15 and KLF16 all inhibit cell growth and transformation mediated by oncogenic KRAS 85. However, in mouse embryonic fibroblasts lacking p21, KLF4 bypasses... WebNational Center for Biotechnology Information oliddy news network

KLF13 suppresses the proliferation and growth of …

Category:KLF13 KLF transcription factor 13 [ (human)] - National …

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Klf13 cancer

Editorial: non-coding rna in immunotherapies and immune regulation

WebKLF13 PATHOLOGY CANCER Dictionary Human pathology PROGNOSTIC SUMMARYi Prognostic marker in renal cancer (favorable) Renal cancer p<0.001 RNA EXPRESSION … Web来源:CANCER-AM CANCER SOC( P 0008-543X E 1097-0142 ) 发表时间: 2024/02. ... 4 Transcription factor KLF13 inhibits AKT activation and suppresses the growth of prostate carcinoma c.. 来源:CANCER BIOMARK( P 1574-0153 E 1875-8592 ) 发表时间: 2024/01.

Klf13 cancer

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WebMay 14, 2024 · As a suppressive transcription factor, KLF13 has been found to be involved in some cell processes of several cancer types. KLF13 expression was inhibited in prostate cancer while its... WebAug 23, 2012 · KLF13 is coimmunoprecipitated with anti-Flag Ab (Fbw7), and Fbw7 coimmunoprecipitates with anti-T7 Ab (KLF13; Figure 3B), showing that KLF13 is …

WebFor instance, KLF13 regulates the life cycle of human papillomavirus in cervical keratinocytes, 38 and KLF13 significantly suppresses cell proliferation and induces apoptosis in pancreatic cancer cells. 39 In addition, KLF13 has been confirmed to inhibit the EMT process of pancreatic cancer cells and suppress the invasion and migration of ... WebJan 4, 2024 · CDK13 interacts with E2F5 in PCa cells. a, Co-immunoprecipitation coupled with mass spectrometry (CoIP-MS) was performed with an anti-CDK13 in PC3 cells to detect the proteins interacting with CDK13, which are shown on the right panel. b, Heat map showing the differential expression (fold changes) of mRNAs between PCa and BPH …

WebKLF13 (BTEB3, FKLF-2, NSLP1, RFLAT-1) protein expression summary. ... Prognostic marker in renal cancer (favorable) Renal cancer p0.001. Cancer specificity i Low cancer specificity: Cell line expression cluster i. Myeloma - Humoral immune response (mainly) Cell ... WebKLF13 is known for its tumor promotive role and has been shown to affect cell differentiation, proliferation, cell cycle and apoptosis (Wu et al. 2024 ). The present study showed that miR-125 has sufficient downregulation in osteosarcoma and directly targets KLF13 to regulate the growth and viability of osteosarcoma cells.

WebNov 20, 2024 · KLF13 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). ... Cancer Biomark, 2024. PMID 29843216; Obesity-related CpG Methylation (cg07814318) of Kruppel-like Factor-13 (KLF13) Gene with …

WebNov 6, 2024 · Zinc protein KLF13 is a tumor-suppressive member of Kruppel-like factors family, and yet the effect of KLF13 on gastric cancer has not been reported. Here, we … oli de botton twitterWebNov 4, 2024 · We identified 68 SV hotspots involving 17 new candidate driver genes, including the therapeutic targets BCMA ( TNFRSF17 ), SLAM7, and MCL1. Catastrophic complex rearrangements termed chromothripsis were present in 24% of patients and independently associated with poor clinical outcomes. olic tucsonWebTaken together, downregulation of KLF13 was observed in fibrotic human/mouse kidneys, and its negative correlation with fibrogenic ECM protein genes suggested a potential role of KLF13 in the pathogenesis of kidney fibrosis. KLF13 inhibits TGF-β signaling by trans-repression in renal TECs is air travel vatable