WebMethods: The PANDA study was a pragmatic, multicentre, double-blind, placebo-controlled randomised trial of patients from 179 primary care surgeries in four UK cities (Bristol, … WebMar 1, 2009 · A randomised controlled trial assessing the severity and duration of depressive symptoms associated with a clinically significant response to sertraline versus placebo, in people presenting to primary care with depression (PANDA trial): study protocol for a randomised controlled trial.

Antidepressant treatment with sertraline for adults with

WebSep 19, 2024 · The so-called "PANDA trial" by Lewis and colleagues enrolled adult patients from 179 primary care centers across four cities in England who had any level of depressive symptoms within the past... WebThe PANDA randomised controlled trial did not find evidence that sertraline led to a clinically important reduction in depressive symptoms at 6 weeks. However, we found strong evidence at 6 and 12 weeks that … huthwaite to sheffield

Sertraline in primary care: Comments on the PANDA trial.

WebThe PANDA trial (“what are the indications for Prescribing ANtiDepressAnts that will lead to a clinical benefit?”)wasaprag-matic multicentre double-blind placebo-controlled randomised trial (Lewis et al., 2024; Salaminios et al., 2024). The original aim of the trial wasto test the clinical effectiveness of sertraline in primary WebOct 24, 2024 · PANDA is a randomised, double-blind, placebo-controlled study in which eligible participants are individually randomised to sertraline or placebo. The sertraline … WebNov 1, 2024 · Sertraline is unlikely to reduce depressive symptoms within 6 weeks in primary care but we observed improvements in anxiety, quality of life, and self-rated mental health, which are likely to be clinically important. ... In the PANDA trial, 115 (46%) participants on sertraline thought they were taking the active drug at 6 weeks compared … huthwaite to nottingham