Webfrom the N-methacryloyl-L-histidine (MHist) and the N-isopropylacrylamide (NIPAAm). They were also obtained in the cross-linked (hydrogel) form, showing a close thermodynamic behaviour as that shown by the corresponding soluble free polymer analogues. Viscometric data revealed that the minimum hydrodynamic volume of the polymer at its isoelectric http://www.expresspolymlett.com/articles/EPL-0000518_article.pdf
Attaching histidine-tagged peptides and proteins to lipid-based ...
WebSep 23, 2024 · An increased number of histidine residues in the terminal branches that buffer the acidic endosomal compartment would allow endosomal lysis and escape of DNA from the endosomes. Similarly, the histidine rich domain in H3K8b would be expected to increase cytosol delivery by enhancing the buffering capacity of the polymer. WebThe pH-sensitive poly ( l -histidine) segments swelled or shrank with the variation of pH to control the release of doxorubicin. 211,226. A fusogenic DOPE liposome was designed with a pH-sensitive poly (ethylene glycol 2000)–diortho ester–distearoyl glycerol conjugate. The sheddable coating, which stabilizes the fusogenic DOPE in liposomes ... dfw runway construction
Chemical vectors for gene delivery: a current review on polymers ...
WebApr 28, 2009 · The terminal cationic groups of a dendritic poly(L-lysine) of the fifth generation (KG5) were substituted with histidine residues (Okuda et al., 2004). The resulting KGH6 dendrimer in which all the terminal amino-acids were histidines showed a buffering effect between pH 4 and pH 6. WebOct 2, 2000 · Since the H-K polymer significantly enhances transfection more than the K-S polymer (Figure 5a), it is evident that the histidine moiety plays an important role in enhancing transfection efficiency. WebJun 1, 2024 · The histidine-rich loop (residues 116-138) has a role in the capture of zinc(II), which is then further delivered into other regions of the protein. For both Zn(II) complexes, histidine residues ... chyme medical term definition